Searchable abstracts of presentations at key conferences in endocrinology

ea0020p657 | Reproduction | ECE2009

Prolonged treatment with N-acetylcysteine and L-arginine restores gonadal function in patients with PCO syndrome

Masha Andi , Manieri Chiara , Dinatale Stefano , Bruno Guido Albino , Ghigo Ezio , Martina Valentino

Introduction: Nitric oxide (NO) plays a wide spectrum of biological actions including a positive role in oocyte maturation and ovulation. Free radicals have been shown elevated in PCOS and therefore would be responsible for quenching NO that, in turn, would play a role in determining oligo or amenorrhea connoting PCOS. We recently demonstrated that the combined administration of N-acetylcysteine (NAC) and arginine (ARG) is able to exert an antioxidant action leading to ...